Randomized controlled trial of oral glutathione supplementation on body stores of glutathione
European Journal of Nutrition, 2015. Daily oral glutathione raised body glutathione stores over six months compared with placebo.
View on PubMedKey benefits
Regulatory activity
No Regulatory Activity
No FDA or clinical-trial activity
Route
Subcutaneous
Often studied away from meals; timing varies by protocol.
Cycle
3–6 months in published oral studies
Typical duration
Storage
Cool, dry place; protect from heat, light and moisture.
Follow vendor guidance
Marketplace
Prices per size, coupon codes, lab reports and shipping.
| Vendor | Price | Coupon | Lab test | Shipping | |
|---|---|---|---|---|---|
LotusPeptide 600 mg | $30.00 Lowest price$0.05/mg | Not on file | 1 business day
| Buy | |
Axon Chems 600 mg | $45.00 $0.07/mg | Not on file | 2–4 days
| Buy | |
Blank Peptides 500 mg | $45.00 $0.09/mg | Not on file | 2–3 days
| Buy | |
NeuroLabs Research 600 mg | $45.14 $0.08/mg | 1 COA | 3–5 days
| Buy | |
Apex Peptides Lab 600 mg | $49.00 $0.08/mg | 1 COA | 2–5 days
| Buy | |
99 Purity Peptides 600 mg | $49.99 $0.08/mg | 1 COA | 3–7 days
| Buy | |
FirstForm Peptides 1500 mg | $49.99 $0.03/mg | Not on file | 2 days
| Buy | |
MsAmino 750 mg | $49.99 $0.07/mg | 1 COA | 2–5 days
| Buy |
What the research reports
What published research has reported so far. These are research findings, not promised results, and most come from settings very different from research-grade use.
Raises body glutathione stores
Main internal antioxidant
Modest skin-lightening effect
Glutathione is a tripeptide made by the body. Controlled trials show oral supplements can raise body stores, and small trials report modest skin effects.
Evidence that extra glutathione, oral or injected, improves health outcomes in healthy people is limited.
Studies
European Journal of Nutrition, 2015. Daily oral glutathione raised body glutathione stores over six months compared with placebo.
View on PubMedJournal of Dermatological Treatment, 2012. Oral glutathione produced a modest reduction in skin pigment versus placebo.
View on PubMedOral glutathione is sold as a dietary supplement and is generally well tolerated. Injectable glutathione is not an FDA-approved drug.
Health regulators in several countries have warned against IV glutathione marketed for skin lightening, citing weak evidence and risks from contaminated or improperly prepared products.
Research-grade material sold online is not an approved drug. Its identity, purity and amount can't be assumed without independent testing, so check the vendor's batch COA.
Pairing
NAC and vitamin C
Commonly combined: NAC supplies building blocks for glutathione, and vitamin C helps recycle it. No harmful interaction is known.
Chemotherapy
Antioxidants may in theory interfere with some cancer treatments that work through oxidative damage. Check with an oncologist.
FAQ
Listings on Pepgrade are educational and marketplace context. Follow local rules and vendor labeling (e.g. RUO).