CJC-1295

CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH) originally developed by ConjuChem Technologies for HIV-associated lipodystrophy. It exists in two forms: with DAC (Drug Affinity Complex) for extended half-life of 5.8-8.1 days, and without DAC (Mod GRF 1-29) for shorter, pulsatile release with a half-life of approximately 30 minutes. Two 2006 randomized, placebo-controlled, double-blind clinical trials (Teichman et al.) demonstrated dose-dependent GH increases of 2-10 fold and IGF-1 increases of 1.5-3 fold in healthy adults aged 21-61. The No DAC version is generally considered the safer choice due to its physiological pulsatile pattern.

Growth Hormone SecretagogueGHRH Receptor ActivationAnti-AgingBody Composition
Vendors
12 vendors
Sizes
2 mg – 10 mg
Intake
Injections

Typical dose

100-300mcg per injection

2-3 times daily

Route

Subcutaneous

Without DAC: Empty stomach, same timing as ipamorelin. With DAC: Time of day less critical due to long half-life.

Cycle

12-16 weeks

Typical duration

Storage

2-8°C

Follow vendor guidance

Marketplace

Vendor listings

12 offers for CJC-1295

VendorPriceRatingShippingCOAAction

Biologix Labs

United StatesFast

$29.99

$6.00/mg

No reviews

2 Days

United States, Canada

None

Certa Peptides

RomaniaFast

$29.99

$14.99/mg

No reviews

1–4 days

Switzerland, United Kingdom +29

1 file

Vertex Labs

United StatesFast

$39.00

$59.00

$7.80/mg

33.9%
No reviews

3 days

United States

2 files

HLX LABS

United StatesFast

$39.99

$8.00/mg

No reviews

2–5 days

United States

1 file

primepepsolutions

United StatesFast

$39.99

$8.00/mg

No reviews

1–3 days

Worldwide

None

bioinfinity

United StatesFast

$45.00

$9.00/mg

No reviews

3–5 days

United States, Puerto Rico

1 file

prpeps

United StatesFast

$45.00

$4.50/mg

No reviews

2 days

United States

None

Crownwell Research

United StatesFast

$48.00

$4.80/mg

No reviews

1-5 days

United States

1 file

What the research reports

Reported research benefits.

Outcomes described across the published literature and ongoing study, not promised results. Read each as research context, not a personal guarantee.

01

Growth hormone secretion

02

Muscle support

03

Recovery

04

Anti-aging research

05

Body composition

Dosage and protocol

How it is typically studied.

CJC-1295 is a growth hormone releasing hormone (GHRH) analog. Without DAC (Mod GRF 1-29), it's dosed multiple times daily; with DAC, once or twice weekly. Half-life without DAC: ~30 minutes; with DAC: 6-8 days.

01 Route

Subcutaneous

02 Example range

100-200mcg

03 Frequency

2-3 times daily

04 Timing

Without DAC: Empty stomach, same timing as ipamorelin. With DAC: Time of day less critical due to long half-life.

Educational reference only. Use clinician guidance for dosing decisions.

Evidence

What the studies actually show.

1

Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects.

CJC-1295 altered serum protein profiles including apolipoprotein A1 and transthyretin as potential GH/IGF-1 biomarkers.

2

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.

CJC-1295 produced sustained dose-dependent increases in GH and IGF-I levels with good safety profile.

3

Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog.

CJC-1295 increased GH and IGF-I levels while preserving normal GH pulsatile secretion patterns.

4

The study of doping market: How to produce intelligence from Internet forums.

Analysis of 13 Internet forums identified 327 doping suppliers and detected emerging peptide products including CJC-1295.

5

Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog.

CJC-1295 demonstrated extended plasma half-life and sustained GH secretion in rats compared to native GRF.

Interactions

How it pairs with other peptides.

IPAMORELIN

Synergistic for GH release. CJC-1295 (GHRH analog) plus Ipamorelin (ghrelin mimetic) amplifies GH pulse through dual-pathway stimulation.

MK-677 (IBUTAMOREN)

Caution: potential for excessive GH/IGF-1 elevation when combining multiple GH secretagogues. Monitor IGF-1 and glucose closely.

BPC-157 Neutral · Emerging

No known negative interaction. Different primary mechanisms. BPC-157 focuses on tissue repair, CJC-1295 on GH release.

FAQ

Frequently asked questions.

CJC-1295 is a growth hormone-releasing hormone (GHRH) analog available in two forms: with DAC (Drug Affinity Complex) for extended half-life, and without DAC (MOD GRF 1-29) for more pulsatile release. It's one of the most established peptides for growth hormone research.