Pep Grading
United States
Romania[Optimization of the treatment of anxiety disorders with selank].
Combined selank and phenazepam treatment reduced benzodiazepine side effects while maintaining anxiolytic efficacy.
Selank
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro, MW ~751.89 g/mol) developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a structural analogue of the immunomodulatory peptide tuftsin with an added Pro-Gly-Pro sequence for stability. Approved in Russia as an anxiolytic and nootropic nasal spray, it crosses the blood-brain barrier to enhance GABAergic neurotransmission, modulate monoamine systems, and regulate neuropeptide Y signaling. A 2008 study of 62 patients with GAD showed Selank comparable to medazepam for anxiety reduction but with no sedation, cognitive impairment, or dependence risk. Half-life is approximately 2-10 minutes.
Nootropic / AnxiolyticNeurotransmitter ModulationCognitive Enhancement
- Vendors
- 17 vendors
- Sizes
- 5 mg – 30 mg
- Intake
- Injections · Nasal Sprays
Typical dose
250-500mcg daily 1-2 times daily
1-2 times daily
Route
Intranasal spray
Can be used morning or evening. Unlike benzodiazepines, selank typically does not cause drowsiness.
Cycle
2-8 weeks Typical duration
Typical duration
Storage
2-8°C Refrigerated
Follow vendor guidance
Marketplace
Vendor listings
17 offers for Selank
| Vendor | Price | Rating | Shipping | COA | Action |
|---|---|---|---|---|---|
Biologix Labs
| $24.98 $31.99 $5.00/mg −21.9% | No reviews | 2 Days United States, Canada | None | |
HLX LABS
| $24.99 $5.00/mg | No reviews | 2–5 days United States | None | |
Amino Club
| $29.95 $3.00/mg | No reviews | 1–4 days United States | None | |
Certa Peptides
| $29.99 $6.00/mg | No reviews | 1–4 days Switzerland, United Kingdom +29 | None | |
idunpeptides
| $29.99 $3.00/mg | No reviews | 3–7 days United States, United Kingdom +1 | None | |
Bionova Peptides
| $30.00 $60.00 $6.00/mg −50% | No reviews | 1–3 days United States | None | |
Trulab Peptides
| $31.00 $6.20/mg | No reviews | 2–5 days Worldwide | None | |
LA Peptides
| $39.99 $4.00/mg | No reviews | 2–5 days United States | None |
What the research reports
Reported research benefits.
Outcomes described across the published literature and ongoing study, not promised results. Read each as research context, not a personal guarantee.
01
Anxiety reduction
02
Cognitive enhancement
03
Stress relief
04
Focus improvement
Dosage and protocol
How it is typically studied.
Selank is an anxiolytic peptide developed in Russia, typically administered intranasally at 200-400mcg per day. It may reduce anxiety without sedation.
01 Route
Intranasal spray, Subcutaneous
02 Example range
200-300mcg
03 Frequency
1-2 times daily
04 Timing
Can be used morning or evening. Unlike benzodiazepines, selank typically does not cause drowsiness.
Educational reference only. Use clinician guidance for dosing decisions.
Evidence
What the studies actually show.
Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia.
Selank showed anxiolytic effects similar to medazepam with additional antiasthenic effects.
A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders.
Selank demonstrated anxiolytic and nootropic effects comparable to phenazepam with improved tolerability.
Functional Connectomic Approach to Studying Selank and Semax Effects.
Selank and Semax alter resting-state functional connectivity in amygdala and prefrontal cortex regions.
Interactions
How it pairs with other peptides.
SEMAX Neutral · Well-documented
Neutral to mildly synergistic. Different neurological targets with no known negative interaction.
FAQ
Frequently asked questions.
Selank is a synthetic peptide developed in Russia combining a tuftsin fragment with additional amino acids, researched for its anxiolytic (anti-anxiety) and nootropic effects.