Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II.
Melanotan II induced penile erection in 85% of men with erectile dysfunction and increased sexual desire.
Melanotan II is a synthetic melanocortin peptide researched for its tanning and libido-enhancing effects.

Typical dose
0.25-1mg
Once daily
Route
Subcutaneous
Administered via subcutaneous injection, typically in the evening. Loading phase involves daily low-dose injections for 1-2 weeks. Once desired effect is reached, frequency reduces to maintenance dosing.
Cycle
4-8 weeks
Typical duration
Storage
2-8°C
Follow vendor guidance
Marketplace
14 offers for Melanotan II
| Vendor | Price | Rating | Shipping | COA | Action |
|---|---|---|---|---|---|
Amino Club
| $14.98 $29.95 $1.50/mg −50% | No reviews | 1–4 days United States | None | |
idunpeptides
| $19.99 $2.00/mg | No reviews | 3–7 days United States, United Kingdom +1 | None | |
Certa Peptides
| $24.99 $5.00/mg | No reviews | 1–4 days Switzerland, United Kingdom +29 | None | |
Biologix Labs
| $27.99 $34.99 $2.80/mg −20% | No reviews | 2 Days United States, Canada | None | |
Synthesis Peptides
| $34.99 $3.50/mg | No reviews | 2–5 days United States | None | |
Giga Compounds
| $36.00 $40.00 $3.60/mg −10% | No reviews | 2 days United States | None | |
Bionova Peptides
| $39.99 $79.99 $4.00/mg −50% | No reviews | 1–3 days United States | None | |
HLX LABS
| $39.99 $4.00/mg | No reviews | 2–5 days United States | None |
What the research reports
Outcomes described across the published literature and ongoing study, not promised results. Read each as research context, not a personal guarantee.
Tanning without sun exposure
Libido enhancement
Skin darkening
Dosage and protocol
Melanotan II is a synthetic melanocortin peptide analog typically administered via subcutaneous injection. Research protocols use a loading phase of 0.25-0.5mg daily, followed by maintenance dosing of 0.5-1mg once or twice weekly. Half-life is approximately 1 hour.
01 Route
Subcutaneous
02 Example range
0.25-0.5mg
03 Frequency
Once daily
04 Timing
Administered via subcutaneous injection, typically in the evening. Loading phase involves daily low-dose injections for 1-2 weeks. Once desired effect is reached, frequency reduces to maintenance dosing.
Educational reference only. Use clinician guidance for dosing decisions.
Evidence
Melanotan II induced penile erection in 85% of men with erectile dysfunction and increased sexual desire.
Melanotan II induced erections in 63% of injections and increased sexual desire versus placebo.
Melanotan II users report tanning and body enhancement motivations with diverse side effects and safety concerns.
Online survey of melanotan users' motivations, acquisition methods, and continuation plans.
Interactions
Melanotan II + TB-500
Often discussed together in recovery-focused research stacks.
Melanotan II + GHK-Cu
Sometimes paired in tissue and skin research conversations.
FAQ
Melanotan II is a synthetic melanocortin peptide researched for its tanning and libido-enhancing effects. It stimulates melanin production and has notable sexual function effects.