No established human clinical evidence
No registered or published human clinical trials evaluating Adamax-specific efficacy, pharmacokinetics, or safety have been identified.
Adamax is a synthetic derivative of Semax featuring an adamantane moiety that enhances blood-brain barrier (BBB) penetration and extends its half-life. Like Semax, it is derived from the ACTH(4-10) fragment but with additional N-acetyl and C-terminal adamantyl modifications. It is proposed to increase BDNF expression more potently than standard Semax and may have stronger nootropic and neuroprotective effects. No human clinical trials exist; all evidence is preclinical or anecdotal from self-experimenters.

Typical dose
300–600 mcg
Once daily (morning)
Route
Intranasal
Administered intranasally, typically in the morning for cognitive enhancement. Some protocols split the dose between morning and early afternoon. Avoid evening dosing if stimulatory effects are noted. Each nasal spray delivers approximately 50-100mcg per actuation.
Cycle
5–7 days on, 2–3 days off
Typical duration
Storage
Store in cool, dry place; protect from light
Follow vendor guidance
Marketplace
5 offers for Adamax
| Vendor | Price | Rating | Shipping | COA | Action |
|---|---|---|---|---|---|
Amino Club
| $89.99 $6.00/mg | No reviews | 1–4 days United States | None | |
American Peptides
| $90.00 $9.00/mg | No reviews | 1-2 days United States | None | |
Crownwell Research
| $99.00 $9.90/mg | No reviews | 1-5 days United States | None | |
LA Peptides
| $99.99 $10.00/mg | No reviews | 2–5 days United States | None | |
Biologix Labs
| $119.98 $149.97 $24.00/mg −20% | No reviews | 2 Days United States, Canada | None |
What the research reports
Outcomes described across the published literature and ongoing study, not promised results. Read each as research context, not a personal guarantee.
Cognitive enhancement
Nootropic effects
Mental clarity
Dosage and protocol
Adamax is an enhanced variant of Semax, a synthetic ACTH(4-10) analog with additional modifications for improved nootropic potency and bioavailability. It is administered intranasally at doses of 100-500mcg per day. Like Semax, it is believed to influence BDNF levels and neurotransmitter activity, with anecdotal reports of stronger cognitive effects.
01 Route
Intranasal
02 Example range
200-300mcg
03 Frequency
Once daily (morning)
04 Timing
Administered intranasally, typically in the morning for cognitive enhancement. Some protocols split the dose between morning and early afternoon. Avoid evening dosing if stimulatory effects are noted. Each nasal spray delivers approximately 50-100mcg per actuation.
Educational reference only. Use clinician guidance for dosing decisions.
Evidence
No registered or published human clinical trials evaluating Adamax-specific efficacy, pharmacokinetics, or safety have been identified.
Interactions
Adamax + Semax
No established clinical interaction or combination benefit. Although Adamax is described as Semax-related, evidence for Semax cannot be assumed to apply to Adamax.
Adamax + Selank
No Adamax-specific clinical interaction data have been established. Claims regarding combined cognitive or anxiolytic effects are anecdotal rather than clinically validated.
FAQ
Adamax is an enhanced variant of Semax, developed for cognitive enhancement research. It is a synthetic peptide with reported nootropic properties.