Adamax

Adamax is a synthetic derivative of Semax featuring an adamantane moiety that enhances blood-brain barrier (BBB) penetration and extends its half-life. Like Semax, it is derived from the ACTH(4-10) fragment but with additional N-acetyl and C-terminal adamantyl modifications. It is proposed to increase BDNF expression more potently than standard Semax and may have stronger nootropic and neuroprotective effects. No human clinical trials exist; all evidence is preclinical or anecdotal from self-experimenters.

Cognitive / NootropicCognitive Enhancement
Vendors
5 vendors
Sizes
5 mg – 40 mg
Intake
Injections · Nasal Sprays

Typical dose

300–600 mcg

Once daily (morning)

Route

Intranasal

Administered intranasally, typically in the morning for cognitive enhancement. Some protocols split the dose between morning and early afternoon. Avoid evening dosing if stimulatory effects are noted. Each nasal spray delivers approximately 50-100mcg per actuation.

Cycle

5–7 days on, 2–3 days off

Typical duration

Storage

Store in cool, dry place; protect from light

Follow vendor guidance

Marketplace

Vendor listings

5 offers for Adamax

VendorPriceRatingShippingCOAAction

Amino Club

United StatesFast

$89.99

$6.00/mg

No reviews

1–4 days

United States

None

American Peptides

United StatesFast

$90.00

$9.00/mg

No reviews

1-2 days

United States

None

Crownwell Research

United StatesFast

$99.00

$9.90/mg

No reviews

1-5 days

United States

None

LA Peptides

United StatesFast

$99.99

$10.00/mg

No reviews

2–5 days

United States

None

Biologix Labs

United StatesFast

$119.98

$149.97

$24.00/mg

20%
No reviews

2 Days

United States, Canada

None

What the research reports

Reported research benefits.

Outcomes described across the published literature and ongoing study, not promised results. Read each as research context, not a personal guarantee.

01

Cognitive enhancement

02

Nootropic effects

03

Mental clarity

Dosage and protocol

How it is typically studied.

Adamax is an enhanced variant of Semax, a synthetic ACTH(4-10) analog with additional modifications for improved nootropic potency and bioavailability. It is administered intranasally at doses of 100-500mcg per day. Like Semax, it is believed to influence BDNF levels and neurotransmitter activity, with anecdotal reports of stronger cognitive effects.

01 Route

Intranasal

02 Example range

200-300mcg

03 Frequency

Once daily (morning)

04 Timing

Administered intranasally, typically in the morning for cognitive enhancement. Some protocols split the dose between morning and early afternoon. Avoid evening dosing if stimulatory effects are noted. Each nasal spray delivers approximately 50-100mcg per actuation.

Educational reference only. Use clinician guidance for dosing decisions.

Evidence

What the studies actually show.

1

No established human clinical evidence

No registered or published human clinical trials evaluating Adamax-specific efficacy, pharmacokinetics, or safety have been identified.

Interactions

How it pairs with other peptides.

Adamax + Semax

No established clinical interaction or combination benefit. Although Adamax is described as Semax-related, evidence for Semax cannot be assumed to apply to Adamax.

Adamax + Selank

No Adamax-specific clinical interaction data have been established. Claims regarding combined cognitive or anxiolytic effects are anecdotal rather than clinically validated.

FAQ

Frequently asked questions.

Adamax is an enhanced variant of Semax, developed for cognitive enhancement research. It is a synthetic peptide with reported nootropic properties.