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TB-500

Research peptide

TB-500

PreclinicalHealing & RecoveryInjury RecoveryAnti-Inflammatory

From

$29.99

Vendors

17

Lab tested

2 COAs

Key benefits

  • Helps cells move into damaged tissue
  • Heart repair in mice
  • Studied for wounds and dry eye
  • Less inflammation in animal studies

TB-500 is a synthetic peptide commonly identified as the N-terminal acetylated LKKTETQ fragment of thymosin beta-4. Research has focused on its molecular relationship to actin, cell migration, angiogenesis, and other cellular response pathways.

Peptide Grading check TB-500 listings, pricing, vendor information, and COA details


Typical dose

2-5mg 2-3x/week

Twice weekly

Route

Subcutaneous

Due to longer half-life, can be dosed 1-2 times per week. Some protocols use every other day during loading phase.

Cycle

6-8 weeks

Typical duration

Storage

2-6°C Refrigerated

Follow vendor guidance

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What the evidence shows

Most evidence is for thymosin beta-4, the full natural protein, which has animal data and a few small human trials (eye drops for dry eye, topical gel for wounds).

TB-500 sold online is usually a short synthetic fragment of that protein, and sometimes the full sequence; vendors vary. The fragment itself has essentially no human research.

Safety and regulatory position

Not FDA-approved

TB-500 is not approved as a drug anywhere. In April 2026 FDA removed it from Category 2, its list of bulk substances flagged for safety concerns in compounding. That is not an approval: an FDA advisory committee reviewed it in July 2026, and no rule allowing pharmacies to compound it has been finalized.

There is no reliable human safety data for injected TB-500. Because it promotes cell migration and blood-vessel growth, the same theoretical tumor concern raised for BPC-157 applies. It is prohibited in sport at all times under the WADA list (S2 peptide hormones and growth factors).

Research-grade material sold online is not an approved drug. Its identity, purity and amount can't be assumed without independent testing, so check the vendor's batch COA.

FAQ

Frequently asked questions.

TB-500 is a synthetic version of the naturally occurring Thymosin Beta-4, one of the most popular peptides for tissue repair and recovery research.